The Astros come into the game following a 7-6 win on Tuesday, which kept their series momentum intact.
In Tuesday’s contest, Altuve finished with one run scored and two strikeouts over five at-bats.
Altuve is not in the lineup on Wednesday, with Brian McTaggart of MLB.com noting simply, “No Altuve today.”
Across 18 games this season, Altuve is batting .288 with two home runs, six RBIs, 13 runs and one stolen base in his 16th MLB season.
The Astros announced their Wednesday starting lineup, and FantasyPros provided a projected lineup for the game, listing players such as Carlos Correa at short, Yordan Alvarez at DH, Isaac Paredes at third, Christian Walker at first, Cam Smith in right field, Yainer Diaz catching, Joey Loperfido in center, Nick Allen at second, and Brice Matthews in left.