Who’s Playing RB for Eagles Today vs. Panthers? Depth Chart Crushed by Injuries — update.

The Philadelphia Eagles will be without Saquon Barkley on Sunday against the Carolina Panthers, and backup Will Shipley won’t be part of the mix either due to injuries crippling Philadelphia’s running back depth. Additionally, starting quarterback Jalen Hurts is sidelined, which will translate into a markedly different offensive approach for the Eagles in Week 6. With a 2-2 Panthers squad coming off a bye week, the opportunity to capitalize is there for Philadelphia, though the absence of key playmakers could significantly influence the flow of the game.

Who’s Available at Running Back for the Eagles?
Philadelphia is activating three running backs for the game. Dameon Pierce is the most likely to carry the lead role after handling a heavy workload when Shipley left Week 5 with an injury (a game Barkley was inactive for). Pierce has a strong past, including a 1,000-yard rookie season with the Houston Texans. However, his recent years have seen a decline in production, and he has largely transitioned to a special-teams role.

Carson Steele, who was active last week, will be active again. Steele is a bruising back who previously played for the Kansas City Chiefs, but his NFL rushing efficiency has been limited. He could be relied upon in short-yardage situations, particularly with Hurts unavailable for the quarterback sneak.

Additionally, the Eagles elevated Jaydon Blue from the practice squad for Sunday. Blue, a 2025 draft pick from Texas, has breakaway speed and previously spent time with the Dallas Cowboys. He was with the Cowboys as a rookie but did not secure a long-term spot, and he has spent this season on Philadelphia’s practice squad. Blue represents a wildcard option, as there’s potential that his burst could earn him a more extended look than practice-squad status would suggest.