Offensively, Wilson appears to be a stabilizing factor for the Cardinals. While the team has struggled overall, Wilson has shown flashes of his potential in big-matchups against the Rams in recent seasons. In the 2025 meeting on December 7, Wilson recorded 11 receptions on 16 targets for 142 yards and two touchdowns. Earlier that season, he posted a 15-catch, 185-yard performance in Week 11 against the San Francisco 49ers. In Week 18, he added five receptions on eight targets for 99 yards and a touchdown, finishing with 16 receptions on 24 targets for 241 yards and three touchdowns across those two games against Los Angeles.
Through five games this season, Wilson has tallied 29 receptions on 51 targets for 288 yards and one touchdown. His output against the Rams in 2025 amounts to a significant portion of his 2026 production so far, underscoring his potential to deliver in this matchup. If he can replicate or exceed those numbers, Wilson could be a catalyst for the offense as Arizona looks to spark its passing game.
The Rams have shown strong pass defense so far this year, leading to questions about how much they can be exploited on Sunday. They rank among the league leaders in passing yards allowed and overall defensive efficiency. However, Wilson’s history against this opponent suggests he could find success again, especially if the Cardinals lean more on the passing game with certain personnel considerations. With key players potentially unavailable or limited, the opportunity for Wilson to step up could be greater this week.
To maximize his impact, Wilson will need to elevate his production and help others on the offense get involved. A strong performance from Wilson, combined with efficient quarterback play and contributions from teammates like Michael McBride and Kendrick Bourne, could help spark a more productive offensive showing at SoFi Stadium. If the unit can convert early opportunities, it may open the door for a more dynamic and consistent offensive display.
In summary, Wilson’s track record against the Rams provides reason for optimism. If he matches or exceeds his previous production and if the Cardinals’ passing attack capitalizes on those chances, he could deliver a standout performance in Week 6 and energize the team going forward.
