San Francisco has made clear it plans to move Aiyuk, but trade movement is unlikely before the NFL draft. General manager John Lynch indicated there’s a chance a deal could happen, though it isn’t considered likely, while head coach Kyle Shanahan said the 49ers are in no hurry and expect the right trade to materialize in due time.
Buffalo has been viewed by some as a plausible destination for Aiyuk, who would provide a true No. 1 outside receiver. Analysts have floated potential trade packages, including multiple mid-round picks, with Aiyuk coming off an ACL injury and a 2025 cap hit in the neighborhood of $11 million, a combination some teams view as manageable with restructures.
Beyond Moore, the Bills have already moved on from Curtis Samuel and face additional personnel decisions at receiver. Brandin Cooks joined late last season and could factor into plans, while Keon Coleman has shown flashes but also faced disciplinary issues, a situation that has drawn scrutiny in the wake of organizational changes.
Buffalo’s passing game remains a priority, as the team looked for improved separation and playmaking from its outside targets. Moore gives them an immediate upgrade, but the Bills will continue weighing Aiyuk and other options against cap implications, draft strategy, and long-term roster balance.
In short, Buffalo’s move for Moore sets the table for a potential Aiyuk pursuit, with the 49ers’ measured approach and the draft timing likely to shape whether a second high-profile wideout lands in Buffalo this offseason.
